Quantifoil R2/4 Holey Carbon Films - Circular

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Density 2.2 Gram per cubic centimeter(g/cm3)
Smell Odorless
Purity >99.9% (Carbon film)
Molecular Formula C
Melting Point >3,500C (Carbon material)
Solubility Insoluble in water and most solvents
Structural Formula Graphitic carbon layer
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Quantifoil R2/4 Holey Carbon Films - Circular Product Specifications

Refractive Rate N/A for solid carbon films
Molecular Weight 12.01 g/mol
Poisonous Yes
Classification Laboratory consumable
Storage Store in a dry, dust-free container at room temperature
Boiling point Sublimates at ~3,600C
Shape Circular grid
EINECS No N/A (not applicable for this product)
Grade Research Grade
Usage Support layer for specimen grids in microscopy
Other Names Quantifoil Holey Carbon Support Film
HS Code 39206919
Ph Level Neutral
Smell Odorless
Type Circular, R2/4 pattern
CAS No 7440-44-0 (carbon)
Density 2.2 Gram per cubic centimeter(g/cm3)
Application Electron microscopy, cryo-EM sample preparation, structural biology, TEM and SEM grid supports
Purity >99.9% (Carbon film)
Form Film on grid
Molecular Formula C
Melting Point >3,500C (Carbon material)
Standard Quantifoil standard, ISO/EN laboratory standards
Solubility Insoluble in water and most solvents
Chemical Name Carbon
Structural Formula Graphitic carbon layer
Main Material Holey carbon film on copper mesh grid

Surface Treatment Uncoated, hydrophobic surface unless plasma treated
Film Thickness ~12-15 nm
Packaging Individually packed in grid storage box
Support Grid Mesh Size 200-mesh standard
Hole Pattern R2/4 - Regular array with 2 m hole diameter and 4 m center-to-center spacing
Grid Diameter 3.05 mm
Compatibility TEM, cryo-TEM, and SEM applications
Resistant To Electron beam, heat within application limits, most chemical solvents
Autoclave Resistant Yes, for short durations
Grid Material Copper (with optional gold or nickel available upon request)
Shelf Life Stable under recommended storage for 2+ years

Quantifoil R2/4 Holey Carbon Films - Circular Trade Information

Payment Terms Paypal, Telegraphic Transfer (T/T), Cash in Advance (CID), Cheque
Main Domestic Market All India

Product Description

Quantifoil R2/4 Holey Carbon Films - Circular

Quantifoils, produced by semiconductor lithographic techniques, are 15 - 20nm thick perforated carbon films with precise, well defined hole sizes, shapes and arrays. Quantifoil support films provide a high percentage of open area in addition to minimising total specimen thickness. Object distortions arising from interactions with the support film are also reduced. They are particularly suited for cryo applications, tomography and low dose microscopy (LEEP).

Circular hole, size 2m dia, separation 4m

Quantifoil type: R2/4

Quantifoils are supplied as 10 grids or 100 grids in a grid box.

Precision Support for Electron Microscopy

The Quantifoil R2/4 Holey Carbon Films provide consistent specimen support for TEM, cryo-EM, and SEM systems. Each film delivers uniform hole size and array, facilitating even sample distribution and high imaging quality. Their optimal thickness and molecular purity support critical research in structural biology and material sciences, meeting strict laboratory standards.

Exceptional Chemical and Thermal Stability

Manufactured from high-purity carbon, these films withstand electron beam exposure, short autoclave cycles, most common solvents, and heat within application limits. The robust structure ensures reliable performance in demanding microscopy workflows, contributing to reproducible and clear imaging results.

Convenience and Compatibility

Packaged individually in secure grid boxes, the Quantifoil R2/4 films are easy to handle and implement in most laboratories. They are compatible with numerous microscopy platforms, supporting contemporary research needs and diverse sample types. Optional gold or nickel grids are available to match specific experiment requirements.

FAQs of Quantifoil R2/4 Holey Carbon Films - Circular:

Q: How should Quantifoil R2/4 Holey Carbon Films be stored for optimal shelf life?

A: Store the films in a dry, dust-free container at room temperature. When properly stored, they remain stable for over two years without compromising performance.

Q: What benefits does the R2/4 hole pattern offer for microscopy?

A: The R2/4 pattern, with 2 m diameter holes spaced 4 m center-to-center, provides excellent sample support and uniform ice thickness in cryo-EM, enabling high-resolution imaging and even specimen distribution.

Q: When should the surface be plasma treated before use?

A: Plasma treatment is recommended when a hydrophilic surface is needed, as the untreated film is hydrophobic. This process enhances sample adhesion and spreading for specific microscopy applications.

Q: Where can these grids be used besides TEM and cryo-TEM?

A: In addition to TEM and cryo-TEM, these grids are suitable for SEM and other forms of electron microscopy requiring stable specimen support and minimal background interference.

Q: What is the process for handling the grids before sample application?

A: Use clean forceps to handle the individually packed grids. If desired, perform plasma treatment, then mount the grid on the specimen holder before applying your sample, ensuring minimal contamination.

Q: What are the key advantages of using copper over gold or nickel grids?

A: Copper grids are standard due to cost-effectiveness and electrical conductivity. However, gold and nickel can be requested for specific experiments requiring enhanced chemical resistance or particular imaging conditions.

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